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Bilateral glossopharyngeal neuropathy following chemo and radiation therapy for a primitive neuroectodermal tumour
Author(s) -
Heir G. M.,
Masterson M.
Publication year - 2016
Publication title -
journal of oral rehabilitation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.991
H-Index - 93
eISSN - 1365-2842
pISSN - 0305-182X
DOI - 10.1111/joor.12347
Subject(s) - medicine , radiation therapy , surgery , neuropathic pain , chemotherapy , pregabalin , anesthesia
Summary This case describes a young adult male patient diagnosed and treated for a primitive neuroectodermal tumour ( PNET ) at 3 years of age. Chemotherapy and radiation therapy used following surgical treatment of this tumour have known neurotoxic complications, some of which have delayed onset. In this case, the patient exhibited sudden onset, persistent bilateral and deep ear pain that was consistent with a neuropathy of the glossopharyngeal nerve occurring 17 years after the completion of therapy for PNET . Treatment with pregabalin was successful with near‐complete resolution of the complaint. The diagnostic certainty in this case is discussed in relation to the current diagnostic criteria for neuropathic pain.