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A 67‐Year‐Old Woman with Polymyalgia Rheumatica and Left Hemispatial Neglect
Author(s) -
Mahfood J. Paul,
Gold Michael,
Gonzalvo America,
Valeriano-Marcet Joanne
Publication year - 1998
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199884222
Subject(s) - medicine , polymyalgia rheumatica , mitotane , edema , radiology , atrophy , dysphagia , pathology , surgery , giant cell arteritis , vasculitis , disease , adrenocortical carcinoma
A 67‐year‐old woman with a diagnosis of polymyalgia rheumatica presented initially wih periods of confusion and incontinence ACT scan of the brain was normal and she was treated with tapering doses of corticosteroids and clinical improvement After a brief period off steroids, the patient presented with a progressive dementia, left‐sided clumsiness, gait disturbances and left hemispatial neglect An MRI at this time demonstrated a large area of edema over the right parietal lobe and intense cortical enhancement A chest CT demonstrated multiple nodules Biopsies of the lung and brain failed to identify any infectious organisms or malignant tissue The leptomeningeal biopsy revealed multiple granulomatous areas with central necrosis and hystiocytic cells consistent with idiopathic hypertrophic pachymeningitis