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Cobalamin Deficiency: MRI Detection of Posterior Columns Involvement and Posttreatment Resolution
Author(s) -
Karacostas Dimitris,
Artemis Nikos,
Bairactaris Chris,
Tsitourides Ioannis,
Milonas Ioannis
Publication year - 1998
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199883171
Subject(s) - cobalamin , medicine , myelopathy , magnetic resonance imaging , vitamin b12 , spinal cord , paralysis , subacute combined degeneration , radiology , pathology , surgery , psychiatry
Cobalamin‐deficient myelopathy is a neurologic disorder manifesting progressive symptoms of paresthesiae and spastic paralysis. The pathologic changes initially involve the posterior columns of the cervical and upper thoracic cord. The authors present the case of a patient with cobalamin deficiency with preferential posterior columns involvement as evidenced by spinal magnetic resonance imaging findings. Marked clinical and radiographic resolution occurred after administration of vitamin B 12 . Early recognition of this specific magnetic resonance pattern is essential, because complete recovery can be achieved with prompt treatment at this reversible stage of the disease. Key words: cobalamin, MRI, myelopathy, vitamin B 12 .