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Primary Diffuse Leptomeningeal Gliomatosis with Signs of Increased Intracranial Pressure and Progressive Meningeal Enhancement on MRI
Author(s) -
Park Justin S.,
Van den Noort Stanley,
Kim Ronald C.,
Walot Irwin,
Licht Harvey
Publication year - 1996
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199664250
Subject(s) - medicine , magnetic resonance imaging , meninges , pia mater , spinal cord , spinal cord neoplasm , radiology , autopsy , lesion , pathology , parenchyma , psychiatry
A 21‐year‐old woman presented with a 5‐month history of meningeal signs and evidence of intracranial hypertension and, as shown by magnetic resonance imaging (MRI), progressively more extensive meningeal enhancement, particularly within the spinal canal. Autopsy disclosed the presence of primary diffuse leptomeningeal gliomatosis with spinal cord predominance, possibly arising within heterotopic leptomeningeal glial tissue in the cervical region. No parenchymal primary lesion was identified. MRI with gadolinium appears to be the imaging modality of choice for the early detection of primary diffuse leptomeningeal neoplasia.