Premium
Quantitative Computed Tomography and Magnetic Resonance Imaging in Aging and Alzheimer's Disease; A Review
Author(s) -
Smith Charles D.
Publication year - 1996
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon19966144
Subject(s) - magnetic resonance imaging , medicine , computed tomography , disease , radiology , preclinical imaging , alzheimer's disease , computed tomographic , pathology , in vivo , microbiology and biotechnology , biology
In recent aging research, quantitative techniques have been used to overcome limitations of qualitative interpretation of magnetic resonance and computed tomographic imaging. The purpose of this review is to summarize imaging results emphasizing quantitative studies using these two modalities in human aging. Magnetic resonance spectroscopy is viewed as an extension of imaging, and results of in vivo spectroscopic studies are included. Because Alzheimer's disease (AD) is closely related to aging, a discussion of quantitative imaging techniques that may distinguish normal elderly from patients with AD is included.