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Increased Middle Cerebral Artery Flow Velocity During the Initial Phase of Cardiopulmonary Bypass May Cause Neurological Dysfunction
Author(s) -
Brillman Jon,
Davis Donalee,
Clark Richard E.,
Price Trevor R. P.,
Lovell Mark R.,
Benckart Daniel A.
Publication year - 1995
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199553135
Subject(s) - medicine , cardiopulmonary bypass , middle cerebral artery , transcranial doppler , cardiology , encephalopathy , artery , stroke (engine) , coronary artery bypass surgery , anesthesia , cerebral arteries , ischemia , mechanical engineering , engineering
One hundred twenty‐seven patients undergoing coronary artery bypass graft surgery were monitored by transcranial Doppler ultrasonography. Five patients had more than 50% increases in middle cerebral artery mean flow velocity during the initial phase (10–120 sec) of cardiopulmonary bypass. Four of these 5 developed neurological complications including stroke and encephalopathy. These results indicate that overperfusion of the basal cerebral arteries during cardiopulmonary bypass procedures may contribute to neurological dysfunction after the surgery