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Magnetic Resonance Evidence of Perineural Metastasis
Author(s) -
Hayat Ghazala,
Ehsan Tajammul,
Selhorst John B,
Manepali Anantha
Publication year - 1995
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199552122
Subject(s) - medicine , perineural invasion , magnetic resonance imaging , trigeminal nerve , cauda equina , nerve root , perineurium , metastasis , pathology , radiology , surgery , spinal cord , cancer , anatomy , peripheral nerve , psychiatry
Contiguous spread along perineural and endoneural spaces, that is, perineural tumor extension, in cutaneous squamous cell carcinoma is fairly common. Infrequently, these tumors spread and involve intracranial structures. One consequence of th1s complication is meningeal carcinomatosis which is underrecognized. Herein described is a patient with recurrent cutaneous squamous cell carcinoma with perineural invasion along the maxillary nerve that was subsequently shown by magnetic resonance imaging to the trigeminal root The patient Initially presented with a cavernous sinus syndrome but despite aggressive treatment, extensive meningeal carcinomatosis and cauda equina dysfunction developed. Awareness of perineural invasion and proper evaluation are crucial. Penneural spread intracranially worsens the prognosis and limits treatment options to palliation.