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Evolution of Crossed Cerebellar Diaschisis in Middle Cerebral Artery Infarction
Author(s) -
Miura Hiroyuki,
Nagata Ken,
Hirata Yutaka,
Satoh Yuichi,
Watahiki Yasuhito,
Hatazawa Jun
Publication year - 1994
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon19944291
Subject(s) - diaschisis , medicine , cerebellum , middle cerebral artery , cerebellar cortex , cerebral infarction , lesion , infarction , frontal lobe , neuroscience , cardiology , anatomy , pathology , ischemia , psychology , myocardial infarction , psychiatry
To elucidate the evolution of crossed cerebellar diaschisis, cerebral oxygen metabolism was measured repeatedly by positron emission tomography (PET) in 35 consecutive patients with unilateral cerebral infarction within the territory of middle cerebral artery. The crossed cerebellar diaschisis was defined as significant when the laterality ratio of cerebral oxygen metabolism between the left and right cerebellar hemispheres exceeded the control range (mean ± 2 standard deviations) as derived from 27 age‐matched normal volunteers. Significant crossed cerebellar diaschisis was observed in 31 patients (89%) on the initial PET studies. Of these 31 patients, 23 with infarcts involving the frontal sensorimotor cortex persistently had crossed cerebellar diaschisis up to 5 years after onset, whereas the diaschisis disappeared in 8 patients with smaller infarcts mainly in the frontal or parietal lobe without recovery of oxygen metabolism in the infarcted areas. These present results suggest that crossed cerebellar diaschisis can exist persistently even in the late stage in those having a lesion involving the cortical pontine‐cerebellar pathways.