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Sequential Positron Emission Tomographic Evaluations of Brain Metabolism in Acute Herpes Encephalitis
Author(s) -
Meyer M. A.,
Hubner K. F.,
Raja S,
Hunter K,
Paulsen W. A.
Publication year - 1994
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199442104
Subject(s) - hypermetabolism , medicine , positron emission tomography , herpes simplex virus , encephalitis , temporal lobe , fluorodeoxyglucose , pathology , nuclear medicine , virology , epilepsy , virus , psychiatry
This first known positron emission tomography report on metabolic changes in acute herpes simplex virus (HSV‐1) encephalitis demonstrates focal hypermetabolism in areas of cerebral cortex adjacent to actively inflamed hippocampus acutely infected with HSV‐1 . When neuropsychiatric symptoms recurred in a previously healthy 61‐year‐old patient 1 month after recovering from acute HSV‐1 encephalitis, repeat positron emission tomography with fluorodeoxyglucose was helpful in ruling out recurrent active infection by showing marked hypometabolism throughout the previously infected temporal lobe.