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Disseminated Diffuse Sclerosis; A Variety of Multiple Sclerosis with Characteristic Clinical, Neuroimaging, and Pathological Findings
Author(s) -
Anselmi Gregory,
Masdeu Joseph C,
Macaluso Claude,
Donnenfeld Hyman
Publication year - 1993
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon199332143
Subject(s) - multiple sclerosis , medicine , neuroimaging , pathological , magnetic resonance imaging , pathology , frontal lobe , histology , radiology , psychiatry
A 20‐year‐old man had a subacute onset of frontal lobe findings and seizures. Computed tomography and magnetic resonance imaging showed three large lesions with mass effect and ring enhancement. Histology and biochemistry confirmed a demyelinating process similar to myelinoclastic diffuse sclerosis but with multiple, noncontiguous lesions. This variety of multiple sclerosis (MS) with clinical, neuroimaging, histological, and treatment characteristics different from typical MS could be termed disseminated diffuse sclerosis .