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Progressive Brainstem Disease in a 32‐Year‐Old Man with a Pituitary Adenoma and Longstanding Diabetes Insipidus
Author(s) -
Sanders Keith A.,
Fetell Michael R.
Publication year - 1992
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon19922125
Subject(s) - medicine , diabetes insipidus , magnetic resonance imaging , pituitary adenoma , brainstem , pathological , differential diagnosis , craniopharyngioma , pituitary gland , pathology , adenoma , radiology , pediatrics , hormone
A 32‐year‐old man who had unexplained diabetes insipidus for 14 years developed hypogonadism and was found to have a pituitary adenoma. Shortly thereafter he noted a progressive brainstem syndrome. Computed tomography and magnetic resonance imaging revealed lesions in the pituitary fossa and brainstem. Dr Keith A. Sanders discusses the differential diagnosis of these lesions, focusing on the significance of diabetes insipidus in a patient with a pituitary tumor, and the specificity of magnetic resonance imaging. Dr Michael R. Fetell discusses the histopathological findings and clinical pathological correlations in this unusual case.