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Brain Myelin Water Fraction and Diffusion Tensor Imaging Atlases for 9‐10 Year‐Old Children
Author(s) -
Morris Sarah R.,
Holmes Richard Davis,
Dvorak Adam V.,
Liu Hanwen,
Yoo Youngjin,
Vavasour Irene M.,
Mazabel Silvia,
Mädler Burkhard,
Kolind Shan H.,
Li David K. B.,
Siegel Linda,
Beaulieu Christian,
MacKay Alex L.,
Laule Cornelia
Publication year - 2020
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon.12689
Subject(s) - medicine , white matter , diffusion mri , fractional anisotropy , corpus callosum , neuroimaging , magnetic resonance imaging , radiology , pathology , psychiatry
Myelin water imaging (MWI) and diffusion tensor imaging (DTI) provide information about myelin and axon-related brain microstructure, which can be useful for investigating normal brain development and many childhood brain disorders. While pediatric DTI atlases exist, there are no pediatric MWI atlases available for the 9-10 years old age group. As myelination and structural development occurs throughout childhood and adolescence, studies of pediatric brain pathologies must use age-specific MWI and DTI healthy control data. We created atlases of myelin water fraction (MWF) and DTI metrics for healthy children aged 9-10 years for use as normative data in pediatric neuroimaging studies.