Premium
Differential Subsampling with Cartesian Ordering for Ultrafast High‐Resolution MRA in the Assessment of Intracranial Aneurysms
Author(s) -
Nael Kambiz,
Drummond James,
Costa Anthony B.,
De Leacy Reade A.,
Fung Maggie M.,
Mocco J
Publication year - 2019
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon.12677
Subject(s) - medicine , aneurysm , radiology , nuclear medicine , magnetic resonance angiography , thrombosis , magnetic resonance imaging , surgery
BACKGROUND AND PURPOSE We aimed to evaluate the feasibility of an ultrafast whole head contrast‐enhanced MRA (CE‐MRA) in morphometric assessment of intracranial aneurysms in comparison to routinely used time‐of‐flight (TOF)‐MRA. METHODS In this prospective single institutional study, patients with known untreated intracranial aneurysm underwent MRA. Routine multislab TOF‐MRA was obtained with a 3D voxel sizes of .6 × .6 × 1 (6‐minute acquisition time). CE‐MRA of whole head was obtained using Differential Subsampling with Cartesian Ordering (DISCO) and 2D Auto‐calibrating Reconstruction for Cartesian imaging with a 3D voxel‐sizes of .75 × .75 × 1 mm 3 during a 6‐second temporal resolution. Morphometric features of intracranial aneurysms, including size, aneurysm sac morphology, and the presence of intraluminal thrombosis, were assessed on both techniques. Statistical analysis was performed using a combination of Kappa test, Bland‐Altman, and correlation coefficient analysis. RESULTS A total of 34 aneurysms in 28 patients were included. Aneurysm size measurements (mean ± SD) were similar between DISCO‐MRA (4.1 ± 2.3 mm) and TOF‐MRA (4.3 ± 2.8 mm) ( P = .27). Bland‐Altman analysis showed a mean difference of .4 mm and there was excellent correlation r = .91 (95% CI: .87‐.96). In six aneurysms (17.6%), TOF‐MRA was nonconfidant to exclude intraluminal thrombosis. In seven aneurysms (20%), TOF‐MRA was unable or nonconfidant in depicting aneurysm sac morphology. CONCLUSIONS Described ultrafast high spatial‐resolution MRA is superior to routinely used TOF‐MRA in assessment of morphometric features of intracranial aneurysms, such as intraluminal thrombosis and aneurysm morphology, and is obtained in a fraction of the time (6 seconds).