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Magnetic Resonance Characteristics and Susceptibility Weighted Imaging of the Brain in Gadolinium Encephalopathy
Author(s) -
Samardzic Dejan,
Thamburaj Krishnamoorthy
Publication year - 2013
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/jon.12067
Subject(s) - medicine , gadolinium , magnetic resonance imaging , fluid attenuated inversion recovery , cerebrospinal fluid , hyperintensity , intrathecal , nuclear medicine , subarachnoid hemorrhage , radiology , parenchyma , pathology , anesthesia , materials science , metallurgy
BACKGROUND AND PURPOSE To report the brain imaging features on magnetic resonance imaging (MRI) in inadvertent intrathecal gadolinium administration. METHODS A 67‐year‐old female with gadolinium encephalopathy from inadvertent high dose intrathecal gadolinium administration during an epidural steroid injection was studied with multisequence 3T MRI. RESULTS T1‐weighted imaging shows pseudo‐T2 appearance with diffusion of gadolinium into the brain parenchyma, olivary bodies, and membranous labyrinth. Nulling of cerebrospinal fluid (CSF) signal is absent on fluid attenuation recovery (FLAIR). Susceptibility‐weighted imaging (SWI) demonstrates features similar to subarachnoid hemorrhage. CT may demonstrate a pseudo‐cerebral edema pattern given the high attenuation characteristics of gadolinium. CONCLUSION Intrathecal gadolinium demonstrates characteristic imaging features on MRI of the brain and may mimic subarachnoid hemorrhage on susceptibility‐weighted imaging. Identifying high dose gadolinium within the CSF spaces on MRI is essential to avoid diagnostic and therapeutic errors.