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Trends in 28‐day and 1‐year mortality rates in patients hospitalized for a first acute myocardial infarction in Norway during 2001–2009: a “Cardiovascular disease in Norway” (CVDNOR) project
Author(s) -
Sulo E.,
Vollset S. E.,
Nygård O.,
Sulo G.,
Igland J.,
Egeland G. M.,
Ebbing M.,
Tell G. S.
Publication year - 2015
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/joim.12266
Subject(s) - medicine , myocardial infarction , mortality rate , retrospective cohort study , disease , cohort study , pediatrics
Objective The aim of this study was to investigate the trends in 28‐day and 1‐year mortality rates in patients hospitalized for a first acute myocardial infarction ( AMI ) in Norway during the period 2001–2009. Potential age group and gender differences in these trends were also examined. Design, subjects and setting In this retrospective nationwide cohort study, patients hospitalized for a first AMI between 2001 and 2009 were identified in the Cardiovascular Disease in Norway 1994–2009 ( CVDNOR ) project and followed for 1 year. Main outcome measures Trends in 28‐day and 1‐year mortality [both all‐cause and cardiovascular disease ( CVD ) mortality] were investigated. Results A total of 115 608 patients (60.6% men) were hospitalized for a first AMI during the study period. Mortality at 28 days was reduced annually by 3.8% overall and by 6.7%, 4.1% and 2.6% in patients aged 25–64, 65–84 and ≥85 years, respectively (all P trend < 0.001). In addition, 1‐year all‐cause mortality was reduced annually by 2.0% overall ( P trend < 0.001) and by 3.7% ( P trend = 0.02), 2.5% ( P trend < 0.001) and 1.1% ( P trend < 0.001) in patients aged 25–64, 65–84 and ≥85 years, respectively. Furthermore, 1‐year CVD mortality was reduced overall by 6.2% annually; a reduction was observed in all age groups. Finally, 1‐year non‐ CVD mortality increased annually overall by 3.9% due to an increase in patients aged ≥65 years. Conclusion Mortaity at 28 days after the first AMI declinedin Norway between 2001 and 2009 in both men and women and in all age groups. All‐cause mortality at 1 year also declined both in men and women due to decreases in CVD mortality rates, whilst non‐ CVD mortality rates increased amongst patients ≥65 years of age.