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Intrauterine fetal death during COVID ‐19 pregnancy: Typical fetal heart rate changes, coagulopathy, and placentitis
Author(s) -
Kato Maya,
Yamaguchi Kyohei,
Maegawa Yuka,
KomineAizawa Shihoko,
Kondo Eiji,
Ikeda Tomoaki
Publication year - 2022
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.15302
Subject(s) - medicine , coagulopathy , fetus , pregnancy , consumptive coagulopathy , obstetrics , covid-19 , coronavirus , disease , infectious disease (medical specialty) , genetics , biology
Although various perinatal outcomes in coronavirus disease 2019 (COVID‐19) pregnancies have been reported, the fetal and neonatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection remain unclear. Several reports of miscarriages and stillbirths have been recorded, but vertical transmission by SARS‐CoV‐2 is considered very rare, and the cause remains unknown. We report a case of a 22‐year‐old uncomplicated Japanese woman infected with SARS‐CoV‐2 during the second trimester, resulting in intrauterine fetal death due to placental insufficiency associated with COVID‐19 placentitis. This report emphasizes the importance of longitudinal assessment of fetal well‐being by fetal heart rate monitoring and early detection of maternal coagulation dysfunction representing SARS‐CoV‐2 inflammation to manage COVID‐19 in pregnancy.