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Innovative approach for first‐trimester fetal organ volume measurements using a Virtual Reality system: The Generation R Next Study
Author(s) -
Wiertsema Clarissa J.,
Sol Chalana M.,
Mulders Annemarie G. M. G. J.,
Steegers Eric A. P.,
Duijts Liesbeth,
Gaillard Romy,
Koning Anton H. J.,
Jaddoe Vincent W. V.
Publication year - 2022
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.15151
Subject(s) - medicine , first trimester , virtual reality , volume (thermodynamics) , obstetrics , fetus , pregnancy , human–computer interaction , computer science , genetics , physics , quantum mechanics , biology
To investigate the reproducibility of first‐trimester fetal organ volume measurements using three‐dimensional (3D) ultrasound and a Virtual Reality system. Methods Within a population‐based prospective cohort study, 3D ultrasound datasets of 25 first‐trimester fetuses were collected by three sonographers. We used the V‐scope application to perform Virtual Reality volume assessments of the fetal heart, lungs, and kidneys. All measurements were performed by two independent researchers. Results Intraobserver analyses for volume measurements of the fetal heart, lungs, and kidneys showed intraclass correlation coefficients ≥0.86, mean differences ≤8.3%, and coefficients of variation ≤22.8%. Interobserver analyses showed sufficient agreement for right lung volume measurements, but consistent measurement differences between observers for left lung, heart, and kidney volume measurements ( p ‐values <0.05). Conclusion We observed sufficient intraobserver reproducibility, but overall suboptimal interobserver reproducibility for first‐trimester fetal heart, lung, and kidney volume measurements using an innovative Virtual Reality approach. In the current stage, these measurements might be promising for the use in research settings. The reproducibility of the measurements might be further improved by novel post‐processing algorithms.