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Maternal risk factors and pregnancy complications associated with low birth weight neonates in preterm birth
Author(s) -
Liu Weiqi,
Liu Qiaoling,
Liu Weiling,
Qiu Cuiqing
Publication year - 2021
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.14830
Subject(s) - medicine , odds ratio , obstetrics , low birth weight , placental abruption , pregnancy , birth weight , confidence interval , incidence (geometry) , risk factor , fetal distress , premature birth , gynecology , fetus , gestational age , genetics , physics , optics , biology
Aim To explore the association between common pregnancy complications and low birth weight (LBW) neonates in preterm birth. Methods The study included 1764 pregnant women who experienced a single birth prematurely at a city hospital in Guangzhou, China between January 1, 2017 and December 31, 2019. A total of 874 normal birth weight neonates and 890 LBW neonates were included. Multivariate logistic regression analysis was conducted to identify and measure risk factors; two‐tailed test was applied, with a p ≤ 0.05 considered statistically significant. Results Hypertension was the primary risk factor of LBW in preterm neonates, odds ratio (OR) = 2.912 ( p < 0.001; 95% confidence interval [CI], 2.044–4.149), followed by hypothyroidism, OR = 1.807 ( p = 0.046; 95% CI, 1.012–3.226), placental abruption, OR = 1.759 ( p = 0.049; 95% CI, 1.002–3.087), reproductive tract infection, OR = 1.746 ( p < 0.001; 95% CI, 1.325–2.301), abnormal amniotic fluid volume, OR = 1.737 ( p = 0.003; 95% CI, 1.202–2.501), and fetal distress OR = 1.690 ( p = 0.012; 95% CI, 1.120–2.551). Conclusion Preventing risk factors, such as hypertension, hypothyroidism, and reproductive tract infections, during pregnancy may reduce the incidence of LBW neonates.