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Effect of interventions in pregnant women with mildly impaired glucose tolerance
Author(s) -
Shindo Ryosuke,
Aoki Shigeru,
Kasai Junko,
Nakanishi Sayuri,
Saigusa Yusuke,
Miyagi Etsuko
Publication year - 2021
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.14783
Subject(s) - medicine , gestational diabetes , impaired glucose tolerance , pregnancy , neonatal hypoglycemia , obstetrics , shoulder dystocia , gestation , diabetes mellitus , hypoglycemia , incidence (geometry) , neonatal respiratory distress syndrome , gestational age , type 2 diabetes , endocrinology , genetics , physics , optics , biology
Aim In 2010, the Japan Society of Obstetrics and Gynecology (JSOG) changed the diagnostic criteria for gestational diabetes mellitus (GDM) to follow the International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria. As a result, many pregnant women with mildly impaired glucose tolerance (IGT) were newly diagnosed with GDM. This study aimed to verify the effects of interventions in pregnant women with mild IGT who were newly diagnosed with GDM based on the present JSOG criteria. Methods We defined mild IGT as a degree of IGT that would be diagnosed as GDM according to the present but not the previous JSOG criteria. We compared pregnancy and delivery outcomes in women with mild IGT who delivered a singleton at 22 weeks of gestation or later, between 2000 and 2009 (untreated group, n = 503) versus between 2011 and 2017 (treated group, n = 781). Results The incidence of GDM‐related composite complications such as macrosomia, shoulder dystocia, neonatal hypoglycemia, neonatal hyperbilirubinemia, and neonatal respiratory distress syndrome was comparable in the untreated and treated groups (10.1% vs. 11.9%, p = 0.11). The pregnancy outcomes were also comparable, except for infant birth weights, which were lower in the treated group than in the untreated group (3014 g vs. 3094 g; p = 0.02). Conclusions Pregnancy outcomes were not affected by the interventions in pregnant women with mild IGT.