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Pulmonary thromboembolism during pregnancy and puerperium: Comparison of survival and death cases
Author(s) -
Takakura Sho,
Tanaka Hiroaki,
Tanaka Kayo,
Katsuragi Shinji,
Hayata Eijiro,
Nakata Masahiko,
Hasegawa Junichi,
Sekizawa Akihiko,
Ishiwata Isamu,
Ikeda Tomoaki
Publication year - 2021
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.14687
Subject(s) - medicine , pregnancy , maternal death , obstetrics , venous thromboembolism , cause of death , retrospective cohort study , postpartum period , surgery , thrombosis , disease , population , genetics , environmental health , biology
Aim In Japan, the frequency of maternal deaths due to obstetric hemorrhage has been decreasing in the last decade, while that resulting from other causes such as pulmonary thromboembolism (PTE) was consistent. To help reduce maternal deaths due to PTE, we investigated PTE during pregnancy and puerperium and compared the survival and death cases, and aimed to find out life and death factors. Methods This study was a retrospective analysis based on a clinical chart review in 407 maternal and perinatal centers. We compared the survival and death cases of PTE during pregnancy and puerperium from 2013 to 2017. Results In PTE during pregnancy, the survival cases underwent significantly earlier diagnoses than the death cases, and thromboprophylaxis was performed in most of both the survival and death cases of PTE during puerperium according to the existing Japanese guidelines; however, only one fourth of the total cases underwent anticoagulation to prevent venous thromboembolism (VTE). Conclusions Early diagnosis of PTE in suspected cases was associated with better survival during pregnancy.