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Case of ovarian steroid cell tumor diagnosed after presenting acute heart failure
Author(s) -
Matsuda Shigeru,
Yamaguchi Yuu,
Kaseki Hanako,
Watanabe Kenichiro,
Ono Shuichi,
Yamamoto Akihito,
Ichikawa Masao,
Akira Shigeo,
Takeshita Toshiyuki
Publication year - 2020
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.14339
Subject(s) - virilization , medicine , hirsutism , heart failure , testosterone (patch) , ovarian tumor , androgen excess , histopathology , surgery , androgen , hormone , pathology , ovarian cancer , cancer , insulin resistance , polycystic ovary , insulin
We report a rare case of an ovarian steroid cell tumor with a diagnosis prompted by heart failure symptoms. A 28‐year‐old Japanese nulligravida/nullipara with a chief complaint of respiratory discomfort during physical exertion and exhibiting heart failure symptoms was referred to our hospital. She also had signs of virilization, including secondary menorrhea since the age of 20, hirsutism and balding. Cushing's syndrome was suspected, and further examinations showed hypertestosteronemia and right ovarian tumor. Symptomatic treatment for heart failure with diuretics and antihypertensives was followed by abdominal right adnexectomy performed due to the androgen‐producing ovarian tumor. The tumor was solid and larger than a fist, and confirmed as a steroid cell tumor through postoperative histopathology. Serum total testosterone levels normalized at day 3 postoperatively, and menstruation resumed 2 months later. Our case was diagnosed due to heart failure symptoms, and its treatment resulted in improvement in virilization signs.