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Mid‐trimester glycosylated hemoglobin levels (HbA1c) and its correlation with oral glucose tolerance test (World Health Organization 1999)
Author(s) -
Dubey Devanshi,
Kunwar Shipra,
Gupta Uma
Publication year - 2019
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.13916
Subject(s) - medicine , postprandial , gestational diabetes , obstetrics , incidence (geometry) , outpatient clinic , diabetes mellitus , observational study , hemoglobin , glucose tolerance test , gestation , impaired glucose tolerance , pregnancy , type 2 diabetes , endocrinology , insulin resistance , physics , biology , optics , genetics
Aim The aim of the present study was to assess the role of hemoglobin A1c (HbA1c) in screening of gestational diabetes mellitus (GDM) and to compare its efficacy with 75 g oral glucose tolerance test (OGTT) (World Health Organization [WHO]) screening criteria. Methods A prospective observational study was performed on a total of 260 women attending antenatal outpatient department of our hospital at 24–28 weeks of gestation. All women underwent 75‐g OGTT testing, and WHO 1999 criteria was used for diagnosis of GDM. Also, a HbA1c test was performed for the same women. Results Prevalence of GDM was found to be 19.6% by OGTT. Mean HbA1c values in GDM was significantly higher than non‐GDM. HbA1c correlated well with both fasting and 2 h postprandial levels but there was better correlation with 2‐h postprandial level. Conclusion The incidence of gestational diabetes is rising in South‐East Asian countries, especially in India. HBA1c could be a potential screening test for GDM.