Premium
Prediction of the efficacy of dinoprostone slow release vaginal insert (Propess) for cervical ripening: A prospective cohort study
Author(s) -
Daykan Yair,
BironShental Tal,
Navve Daniella,
Miller Netanella,
Bustan Mor,
SukenikHalevy Rivka
Publication year - 2018
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.13715
Subject(s) - dinoprostone , ripening , medicine , obstetrics , prospective cohort study , vaginal delivery , gestational age , pregnancy , gynecology , surgery , prostaglandin e2 , biology , genetics , food science
Aim To evaluate factors predictive of the success of dinoprostone slow release vaginal insert for cervical ripening. Methods A total of 169 women who underwent cervical ripening with dinoprostone slow release vaginal insert were included in the study cohort. The correlation between parameters present before cervical ripening with dinoprostone slow release and its success, as well as complications and adverse outcomes were analyzed. Results Dinoprostone slow release vaginal insert was successful in achieving vaginal delivery in 148 of 169 (87.6%), while sufficient ripening was achieved in 140 (83%) cases. Factors associated with successful vaginal delivery were multiparity and younger gestational age at delivery. Factors predictive of the success of cervical ripening with dinoprostone slow release vaginal insert were lower body mass index (BMI), higher parity and perceived contractions prior to insertion. Intrauterine growth restriction was associated with a significant risk for dinoprostone insert removal. Neonatal outcomes were similar in cases of successful or failed ripening. Conclusion The success of cervical ripening with dinoprostone slow release vaginal insert can be predicted by factors that can be recognized at admission.