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Perinatal outcomes following labor induction with dinoprostone in pregnancies with borderline amniotic fluid index at term: A clinical observation study
Author(s) -
Yin Heng,
Zhao Lei,
Lin Ying,
Wang Ying,
Hu Yaping,
Sun Guoqiang,
Xiao Mei
Publication year - 2018
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.13682
Subject(s) - medicine , amniotic fluid index , obstetrics , fetal distress , odds ratio , gestational age , neonatal intensive care unit , labor induction , meconium , amniotic fluid , birth weight , gestation , confidence interval , apgar score , gynecology , pregnancy , fetus , oxytocin , pediatrics , genetics , biology
Aim To compare perinatal outcomes of dinoprostone for induced labor in pregnancies with a borderline versus normal amniotic fluid index (AFI) at term, and to investigate the related factors affecting outcomes of cesarean section. Methods The retrospective study was carried out in Hubei Maternal and Child Health Hospital with singleton pregnancies of 37–42 weeks’ gestation from January to August 2016. A total of 992 subjects were divided into two groups: borderline AFI group ( n =125) with 5 < AFI ≤ 8 and normal AFI group ( n = 867) with 8 < AFI ≤ 24. Results Time to delivery ( P =0.004) and use of oxytocin augmentation ( P = 0.011) were significantly lower in pregnancies with borderline AFI. There were no significant differences between the two groups in terms of delivery mode, time to onset of labor, fetal distress, Apgar scores, meconium‐stained amniotic fluid, birth weight, or incidences of admission to neonatal intensive care unit (NICU). Gestational hypertension and birth weight were the major factors affecting outcomes of cesarean section in the borderline group (odds ratio [OR] = 13.61, 95% confidence interval [CI] 1.96–94.49, P =0.008 and OR = 1.003, 95% CI 1.001–1.005, P =0.001, respectively). Maternal age (OR = 1.12, 95% CI 1.06–1.19, P < 0.001), parity (OR = 7.57, 95% CI 3.05–18.76, P < 0.001), biparietal diameter (OR = 0.55, 95% CI 0.33–0.91, P = 0.021), and meconium‐stained amniotic fluid (OR = 1.56, 95% CI 1.12–2.17, P = 0.009) were related factors in the normal group. Conclusion The perinatal outcomes of dinoprostone for induced labor are comparable between the two groups. Gestational hypertension and birth weight are factors related to outcomes of cesarean section in the borderline group.