Premium
Psychological distress in post‐partum women after non‐invasive prenatal testing ( NIPT ) in Japan
Author(s) -
Takeda Eri,
Suzumori Nobuhiro,
Ebara Takeshi,
Yotsumoto Junko,
Kumagai Kyoko,
Oseto Kumiko,
Numabe Hironao,
SugiuraOgasawara Mayumi
Publication year - 2018
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.13483
Subject(s) - medicine , post partum , intracytoplasmic sperm injection , obstetrics , distress , logistic regression , psychological distress , mental health , gynecology , assisted reproductive technology , pregnancy , clinical psychology , psychiatry , in vitro fertilisation , infertility , genetics , biology
Aim The purpose of this study was to clarify the characteristics of psychological mental distress in post‐partum women after non‐invasive prenatal testing (NIPT) in Japan. Methods Psychological mental distress was assessed using the Kessler Psychological Distress Scale (K6). We compared patients with (i) low pre‐NIPT K6 and low post‐partum K6 scores (control group), and (ii) low pre‐NIPT K6 and a high post‐partum K6 scores (case group). Results Among the 697 women who underwent NIPT, 29 (4.2%) had low pre‐NIPT K6 and high post‐partum K6 scores (case group) and 668 (95.8%) had low pre‐NIPT K6 and low post‐partum K6 scores (control). Among women with negative NIPT findings, post‐partum women with a high K6 score were compared to a control group of women with a low K6 score. Logistic regression analysis showed that primiparity ( P = 0.007), low birthweight ( P = 0.005) and use of intracytoplasmic sperm injection ( P = 0.02) and assisted reproductive technology ( P = 0.05) were significantly different between the groups. Conclusion Even if women do not feel mental distress before NIPT, they may develop mental stress post‐partum. In particular, primipara women who conceived through assisted reproductive technology (especially intracytoplasmic sperm injection) and gave birth to a low birthweight baby were more susceptible to developing post‐partum distress. Thus, it is important to educate women that support is available, with consultation with other healthcare professionals during genetic counseling if necessary. Further studies are needed in order to determine the factors associated with post‐partum mental distress.