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Primary osteosarcoma of the uterine cervix: A case report
Author(s) -
Tsuji Keita,
Watanabe Yoh,
Tokunaga Hideki,
Shimada Muneaki,
Watanabe Mika,
Yaegashi Nobuo
Publication year - 2017
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.13443
Subject(s) - medicine , cervix , hysterectomy , abdominal hysterectomy , osteosarcoma , metastasis , biopsy , surgery , radiology , cancer , pathology
Primary osteosarcoma of the uterine cervix is extremely rare. Only 20 cases have been reported, 19 of which originated in the uterine corpus. We report a case of primary uterine cervical osteosarcoma with pulmonary metastasis in a 30‐year‐old nulligravida woman. The initial diagnosis was carcinosarcoma of the uterine cervix, as detected by cervical cytology and biopsy analysis. We performed a total hysterectomy, bilateral salpingo‐oophorectomy and colostomy without macroscopic residual tumors in the abdominal cavity, but pelvic recurrent tumors appeared 14 days postoperatively. Both recurrent and metastatic tumors were effectively reduced by combination therapy of adriamycin with ifosfamide; however, the patient died as a result of of disease progression nine months after her first visit to our department.