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Differences in autonomic neural activity during exercise between the second and third trimesters of pregnancy
Author(s) -
Nakagaki Akemi,
Inami Takayuki,
Minoura Tetsuji,
Baba Reizo,
Iwase Satoshi,
Sato Motohiko
Publication year - 2016
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12990
Subject(s) - medicine , third trimester , autonomic nervous system , pregnancy , gestational age , heart rate , heart rate variability , cycle ergometer , cardiology , gestation , obstetrics , physical therapy , blood pressure , genetics , biology
Abstract Aim To test the hypothesis that autonomic neural activity in pregnant women during exercise varies according to gestational age. Methods This cross‐sectional study involved 20 healthy women in their second ( n = 13) or third ( n = 7) trimester of pregnancy. Incremental cardiopulmonary exercise testing was performed with an electromagnetic cycle ergometer. Heart rate variability was analyzed by frequency analysis software. Results The low‐frequency to high‐frequency (LF/HF) ratio, an indicator of the sympathetic nervous system, was significantly higher in third trimester than in second trimester subjects ( P < 0.05) at 1, 2, and 3 min of incremental exercise testing. In contrast, the HF/total power ratio, an indicator of rapidly acting parasympathetic activity, was significantly higher in second trimester than in third trimester subjects ( P < 0.05) at 2 and 3 min. In addition, a negative correlation was found between gestational age and the ‘accumulation half‐time’ of the LH/HF ratio, the time point at which the sum of the LF/HF ratio reached 50% of that accumulated in the total 6 min of exercise testing ( r = −0.49, P = 0.028). Conclusions The autonomic response to exercise in pregnant women differs between the second and third trimesters. These differences should be considered when prescribing exercise to pregnant women.