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Combined large‐cell neuroendocrine carcinoma and endometrioid adenocarcinoma of the endometrium: A case report and survey of related literature
Author(s) -
Matsumoto Harunobu,
Nasu Kaei,
Kai Kentaro,
Nishida Masakazu,
Narahara Hisashi,
Nishida Haruto
Publication year - 2016
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12881
Subject(s) - medicine , neuroendocrine carcinoma , endometrium , carcinoma , adenocarcinoma , oncology , gynecology , general surgery , cancer
Primary large‐cell neuroendocrine carcinoma of the endometrium is extremely rare and has a poor prognosis. This report describes a case of combined large‐cell neuroendocrine carcinoma and endometrioid adenocarcinoma of the endometrium diagnosed as stage IIIA. The patient underwent surgery and chemotherapy and has been well with no evidence of disease for 20 months. The optimal treatment for this rare tumor has not been established. Considering its rarity and variability, it is difficult to establish an evidence‐based therapeutic regimen.