Prenatal diagnosis and follow‐up of a case of branchio‐oto‐renal syndrome displays renal growth impairment after the second trimester

Branchio‐oto‐renal syndrome combines branchial arch defects, hearing impairment and renal malformations or hypoplasia. Due to the high phenotypic variability, prenatal diagnosis has a limited prognostic value in mutation‐positive cases. We report the first branchio‐oto‐renal syndrome molecular prenatal diagnosis and ultrasonographic follow‐up, showing a normal renal growth until the 24th week of pregnancy, a growth deceleration during the third trimester and a renal volume recovery during the first months of life.