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Acute presentation of gestational diabetes insipidus with pre‐eclampsia complicated by cerebral vasoconstriction: A case report and review of the published work
Author(s) -
Mor Amir,
Fuchs Yael,
Zafra Kathleen,
Haberman Shoshana,
Tal Reshef
Publication year - 2015
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12694
Subject(s) - medicine , reversible cerebral vasoconstriction syndrome , eclampsia , pregnancy , vasoconstriction , gestation , diabetes insipidus , gestational diabetes , complication , obstetrics , preeclampsia , pediatrics , presentation (obstetrics) , biology , genetics
Gestational diabetes insipidus (GDI) is a rare, self‐limited complication of pregnancy. As it is related to excess placental vasopressinase enzyme activity, which is metabolized in the liver, GDI is more common in pregnancies complicated by conditions associated with liver dysfunction. We present a case of a 41‐year‐old woman at 38 weeks’ gestation who presented with pre‐eclampsia with severe features, including impaired liver function and renal insufficiency. Following cesarean section she was diagnosed with GDI, which was further complicated by cerebral vasoconstriction as demonstrated by magnetic resonance angiography. This case raises the possibility that cerebral vasoconstriction may be related to the cause of GDI. A high index of suspicion of GDI should be maintained in patients who present with typical signs and symptoms, especially in the setting of pregnancy complications associated with liver dysfunction.