Premium
Uterine cervical cancer with brain metastasis as the initial site of presentation
Author(s) -
Sato Yumi,
Tanaka Kei,
Kobayashi Yoichi,
Shibuya Hiromi,
Nishigaya Yoshiko,
Momomura Mai,
Matsumoto Hironori,
Iwashita Mitsutoshi
Publication year - 2015
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12668
Subject(s) - medicine , parametrium , brain metastasis , cervical cancer , metastasis , vomiting , lesion , radiology , radiation therapy , uterine cancer , cancer , pathology , surgery
Brain metastasis from uterine cervical cancer is rare, with an incidence of 0.5%, and usually occurs late in the course of the disease. We report a case of uterine cervical cancer with brain metastasis as the initial site of presentation. A 50‐year‐old woman with headache, vertigo, amnesia and loss of appetite was admitted for persistent vomiting. Contrast enhanced computed tomography showed a solitary right frontal cerebral lesion with ring enhancement and uterine cervical tumor. She was diagnosed with uterine cervical squamous cell carcinoma with parametrium invasion and no other distant affected organs were detected. The cerebral lesion was surgically removed and pathologically proved to be metastasis of uterine cervical squamous cell carcinoma. The patient underwent concurrent chemoradiotherapy, followed by cerebral radiation therapy, but multiple metastases to the liver and lung developed and the patient died 7 months after diagnosis of brain metastasis.