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C andida glabrata sepsis associated with chorioamnionitis in an IVF twin pregnancy: Should we deliver?
Author(s) -
Tan Shu Qi,
Ng Oon Tek,
Khong Chit Chong
Publication year - 2015
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12656
Subject(s) - medicine , chorioamnionitis , pregnancy , fetus , amniocentesis , obstetrics , sepsis , immunology , prenatal diagnosis , biology , genetics
We report a case of in vitro fertilization (IVF)‐acquired C andida glabrata chorioamnionitis successfully treated through systemic maternal antifungal treatment prior to delivery. To the best of our knowledge, this is the first case of its kind in the literature. C. glabrata chorioamnionitis in pregnancy is rare, but the current literature suggests a very high fetal fatality in such cases. It is known to have an association with cervical stitch, amniocentesis, chorionic villous sampling, and assisted reproductive techniques such as IVF. Given the increasing global use of artificial reproductive techniques, it is important to raise awareness of this condition and highlight its potential complications. Early recognition of possible fetal infection could enable early initiation of systemic antifungal treatment. It would be prudent to consider early delivery once fetal maturity is achieved despite normal fetal monitoring.