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P seudo‐ M eigs' syndrome associated with hydropic degenerating uterine leiomyoma: A case report
Author(s) -
Oguma Tomoko,
Yamasaki Noriyuki,
Nakanishi Kentaro,
Kinoshita Dan,
Mitsuhashi Tamae,
Nakagawa Shoko
Publication year - 2014
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12299
Subject(s) - medicine , uterine leiomyoma , pleural effusion , ascites , leiomyoma , myoma , pathogenesis , hysterectomy , vascular endothelial growth factor , pathology , gynecology , gastroenterology , surgery , uterus , vegf receptors
Pseudo‐ M eigs' syndrome secondary to uterine leiomyoma is a rare entity. A 50‐year‐old Japanese woman presented with a 3‐month history of shortness of breath. Chest X ‐ray and magnetic resonance imaging revealed massive right pleural effusion, ascites and a large subserosal uterine myoma. She underwent a total abdominal hysterectomy with bilateral salpingo‐oophorectomy. The pathology was consistent with a benign leiomyoma. The ascites and pleural effusion rapidly disappeared postoperatively. The serum interleukin‐6 level was 3.9 pg/mL before surgery and declined to 1.6 pg/mL postoperatively. Previous published work has demonstrated that vascular endothelial growth factor and interleukin‐6 may play a role in the pathogenesis of M eigs' syndrome and that vascular endothelial growth factor may contribute to the development of pseudo‐ M eigs' syndrome due to metastatic ovarian cancer. This is the first E nglish‐language study showing the possibility that interleukin‐6 is relevant to the pathogenesis of pseudo‐ M eigs' syndrome caused by degenerating uterine leiomyoma.