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Rare case of peritoneal complete hydatidiform mole
Author(s) -
Ota Hajime,
Oda Chikara,
Hayashi Masaki,
Mikoshiba Takao,
Kushima Miki
Publication year - 2014
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12287
Subject(s) - medicine , conceptus , gestational sac , ectopic pregnancy , uterus , laparotomy , immunohistochemistry , peritoneum , pathology , surgery , pregnancy , fetus , biology , genetics
A 23‐year‐old woman, gravida 1, para 1, was transferred to our hospital with acute lower abdominal pain and vital signs consistent with shock. Her urine concentration of human chorionic gonadotrophin was 8000 mIU/mL. Transvaginal ultrasound revealed an echo‐free space with mosaic echo pattern in the right adnexal area and no gestational sac in the uterus. With a preoperative diagnosis of ruptured ectopic pregnancy, emergency laparotomy was performed. The rectouterine pouch was filled with many clots containing small amounts of villous tissue. After removal of the conceptus, which was infiltrating into the peritoneum of the Pouch of Douglas, bleeding was controlled by Argon laser. Histological examination of the conceptus by immunohistochemical staining with p57 kip2 showed features of complete hydatidiform mole. This case demonstrates that the peritoneum in the P ouch of D ouglas is a possible site of ectopic complete hydatidiform mole occurrence and that immunohistochemical stain is useful to confirm the diagnosis of ectopic complete hydatidiform mole.