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Exposure to ambient air pollutants and spontaneous abortion
Author(s) -
Moridi Maryam,
Ziaei Saeideh,
Kazemnejad Anoshirvan
Publication year - 2014
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12231
Subject(s) - abortion , medicine , gestation , air pollutants , pregnancy , pollutant , obstetrics , case control study , air pollution , chemistry , genetics , organic chemistry , biology
Aim This study aimed to evaluate the correlation between ambient concentrations of air pollutants and first‐trimester spontaneous abortion. Material and Methods This was a retrospective case–control study, which was conducted on 296 women from J une 2010 to F ebruary 2011 in T ehran, I ran. Cases were 148 women who experienced a spontaneous abortion before 14 weeks of gestation while the controls were 148 pregnant women after 14 weeks of gestation and groups were matched on sociodemographics and obstetrics characteristics. The samples were recruited randomly from 10 hospitals. In total, pollutants concentrations were collected at 29 stations hourly throughout the study area. We estimated the mean exposure for each participant and investigated the association between spontaneous abortion and ambient pollutants. Results Findings demonstrated that the average of ambient air pollutants in the cases was significantly higher than in the controls ( P < 0.05). The odd ratios of abortion in the areas with higher concentrations of CO , NO 2 , O 3 and PM 10 were 1.98, 0.96, 0.94 and 1.01, respectively ( P < 0.05). Also, the model showed that there was no significant association between prenatal exposures to SO 2 and abortion ( P > 0.05). Conclusions Our findings suggest that pregnant women exposed to ambient air pollutants may be at increased risk of spontaneous abortion. Confirmation by further research is needed.