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Triple simultaneous primary invasive gynecological malignancies: A case report
Author(s) -
Takatori Eriko,
Shoji Tadahiro,
Miura Yuki,
Takeuchi Satoshi,
Uesugi Noriyuki,
Sugiyama Toru
Publication year - 2014
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12199
Subject(s) - medicine , carboplatin , adenocarcinoma , cervical cancer , hysterectomy , serous fluid , pathological , cancer , regimen , stage (stratigraphy) , ovarian cancer , endometrial cancer , gynecology , oncology , pathology , chemotherapy , cisplatin , paleontology , biology
Double gynecologic cancer (primary cancers in two organs) is relatively rare. However, triple gynecologic cancer (primary cancers in three organs) is extremely rare. We experienced a case of triple cancer, with primary cervical, endometrial and ovarian cancers, each showing different histopathological features. A 50‐year‐old woman with a preoperative diagnosis of cervical cancer stage I b1 with a pathological diagnosis of mucinous adenocarcinoma underwent radical hysterectomy. The pathological diagnoses of the extracted masses were endometrioid adenocarcinoma in the uterine corpus and serous adenocarcinoma in the left ovary. Consequently, triple cancer was diagnosed. After the operation, six cycles of a paclitaxel/carboplatin regimen were administered, and no relapse of the cancers has been observed to date. To our knowledge, this is only the second case report in the international literature of concurrent gynecologic triple cancers of epithelial origin; that is, invasive cervical, endometrial and ovarian cancers, each with different histopathological features.