Premium
Neonatal outcome in infants of chronically hypertensive mothers
Author(s) -
Ono Yoshihisa,
Takagi Kenjiro,
Seki Hiroyuki,
Takai Yasushi,
Samejima Koki,
Matsunaga Shigetaka,
Matsumura Hideyoshi
Publication year - 2013
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12041
Subject(s) - medicine , outcome (game theory) , pediatrics , obstetrics , mathematics , mathematical economics
Aim We investigated the neonatal outcome in chronically hypertensive patients with controlled hypertension, uncontrollable hypertension, or superimposed pre‐eclampsia. Material and Methods The study included 120 patients who had chronic hypertension and were divided into three groups for which the perinatal and neonatal outcomes were retrospectively compared: pre‐eclampsia superimposed on chronic hypertension ( SP : n = 28), chronic hypertension with severe hypertension uncontrolled in spite of intravenous or multiple oral antihypertensive medications in the latter half of pregnancy ( uCH : n = 44), and chronic hypertension with controlled to mild hypertension with or without medication ( cCH : n = 48). Results Preterm birth rate incidence was significantly higher in the SP and uCH groups than in the cCH group ( P < 0.05 for both). The incidence rates of low birthweight, very low birthweight, and extremely low birthweight for the groups were as follows: SP > uCH > cCH . Admission to the neonatal intensive care unit was significantly higher in the uCH and SP groups than in the cCH group ( P < 0.05 for both). Conclusion Like superimposed pre‐eclampsia, uncontrolled chronic severe hypertension during late pregnancy results in a poorer neonatal outcome than controlled chronic mild hypertension. We conclude that absolute blood pressure can be used as a predictor of clinical outcome in pregnant chronic hypertension patients.