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Single indications of induction of labor with prostaglandins and risk of cesarean delivery: A retrospective cohort study
Author(s) -
Gerli Sandro,
Favilli Alessandro,
Giordano Claudia,
Bini Vittorio,
Di Renzo Gian Carlo
Publication year - 2013
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/jog.12000
Subject(s) - medicine , labor induction , logistic regression , pregnancy , retrospective cohort study , obstetrics , cohort , induction of labor , cesarean delivery , univariate analysis , parity (physics) , multivariate analysis , bishop score , gynecology , oxytocin , surgery , genetics , physics , particle physics , biology
Abstract Aim To determine the risk of cesarean delivery after induction of labor with prostaglandins and to establish if this is influenced by a single indication of induction of labor or any intrinsic characteristic of the woman or labor. Material and Methods A retrospective cohort study was carried out. Three hundred and twenty‐four pregnant women who underwent pharmacological induction of labor with prostaglandins were divided into nine groups through indication of labor induction. Statistical analysis was assessed with the K olmogorov– S mirnov test to assess the normal distribution of variables, K ruskal– W allis test for comparisons of non‐parametric continuous variables, univariate analysis to compare cesarean delivery rates and multivariate logistic regression. Results The risk of cesarean section was significantly higher only in prolonged pregnancy ( OR = 1.98; 95% CI : 1.18–3.34). Elective induction was associated with the lowest risk of cesarean section ( OR = 0.46; 95% CI : 0.26–0.81). Maternal age and was directly related ( OR = 1.087; 95% CI : 1.016–1.164), while parity ( OR = 0.123; 95% CI : 0.051–0.332), B ishop score ( OR = 0.703; 95% CI : 0.571–0.884), and duration of labor ( OR = 0.995; 95% CI : 0.993–0.998) were inversely correlated with cesarean delivery. Conclusion Cesarean delivery rate is not significantly influenced by any indication of induction of labor with prostaglandins, except for prolonged pregnancy. Elective induction is associated with the lowest risk of cesarean section. Increasing maternal age, low parity, low B ishop score and low duration of labor are at higher risk of cesarean section.