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Clinical Evidence for Stunned Myocardium After Coronary Artery Bypass Surgery
Author(s) -
Kloner Robert A.,
Przyklenk Karin,
Kay Gregory L.
Publication year - 1994
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.1994.9.3s.397
Subject(s) - medicine , preload , cardiology , cardiopulmonary bypass , afterload , artery , ischemia , coronary artery bypass surgery , ventricular function , bypass surgery , hemodynamics
Stunned myocardium is defined as postischemic dysfunction of viable myocardium. This phenomenon was initially described in animal models of brief ischemla followed by reperfusion, but is becoming increasingly recognized in clinical situations. One of these situations is ventricular dysfunction following coronary artery bypass surgery. Several clinical reports have demonstrated depressed ventricular function in the initial hours after coronary artery bypass surgery: this dysfunction is usually resolved within 24 to 48 hours, and does not appear to be dependent upon alterations in preload, afterload, or temperature. New therapies for improving postischemic myocardial function following cardiopulmonary bypass are under investigation.