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Isolated vascular rings in the era of high prenatal detection rates: Demographics, diagnosis, risk factors, and outcome
Author(s) -
Evans William N.,
Acherman Ruben J.,
Ciccolo Michael L.,
Lehoux Juan,
Berthoty Dean,
Mayman Gary A.,
Restrepo Humberto
Publication year - 2021
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.15414
Subject(s) - medicine , confidence interval , concordance , relative risk , risk factor , demographics , intracardiac injection , obstetrics , demography , sociology
Objective We reviewed our center's isolated vascular ring data. Methods Inclusion criteria were patients born in Nevada between June 2015 and July 2020 with situs solitus, levocardia, atrioventricular and ventriculoarterial concordance, and no significant intracardiac malformations. Results We identified 95 patients. Of the 95, 56 (59%) were female ( p = .033). For the study period, there were approximately 180,000 live births, for a prevalence of 5.3 isolated vascular rings per 10,000 live births. Of the 95, 78 (82%) were prenatally diagnosed. Of the 95, 63 (66%) were products of high‐risk pregnancies ( p = .0001). Additionally, we found advanced maternal age was an isolated vascular ring risk factor (relative risk ratio, 2.7; 95% confidence interval, 1.8, 4.1; p < .00001). Conclusions Isolated vascular rings are relatively common cardiovascular malformations and more common in females. High prenatal detection rates are achievable. Further, the majority with isolated vascular rings are products of high‐risk pregnancies, and advanced maternal age is a statistically significant occurrence risk factor.