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Management of malperfusion: New York approach and outcomes
Author(s) -
Iannacone Erin,
Robinson Bryce,
Rahouma Mohamed,
Girardi Leonard
Publication year - 2021
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.15025
Subject(s) - medicine , aortic dissection , cardiology , myocardial infarction , aortic aneurysm , aneurysm , cohort , univariate analysis , surgery , aorta , multivariate analysis
Background and Aim Aortic branch malperfusion complicates up to one‐third of acute type A aortic dissection (ATAAD), and it is a strong predictor of poor outcomes. We analyzed our results for the surgical management of this high‐risk cohort. Methods We queried our aortic database for consecutive patients undergoing ATAAD repair. Those presenting with malperfusion were compared with those without. Outcomes were compared using univariate and multivariate analysis. Results From 1997 to 2019, a total of 336 patients underwent ATAAD repair. A total of 97 ATAAD patients presented with malperfusion. Malperfusion patients were more likely to be male (54.8% vs. 75.3%; p  = .001), have had a prior myocardial infarction (11.9% vs. 26.8%; p  = .001), to present with preoperative renal dysfunction (22.2% vs. 54.6%; p  < .001), and to present with shock (12.6% vs. 28.9%; p  = .001). The malperfusion group more often underwent coronary artery bypass grafting (5.4% vs. 24.7%; p  < .001), and required additional noncardiac procedures 10.3% of the time. Operative mortality (0.8% vs. 15.5%; p  < .001) and major adverse events (MAEs) (7.6% vs. 20.6%; p  = .001) were both greater for the malperfusion patients. Ejection fraction, diabetes, and malperfusion were predictors of MAEs. Cerebral, coronary, mesenteric, and multiple vascular bed malperfusion were predictors of MAEs, while extremity, renal, and spinal were not. Conclusion Improving outcomes for this high‐risk cohort requires rapid diagnosis and reversal of ischemia while minimizing the risk of aortic rupture, irrespective of the strategic approach.

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