Premium
The prognostic value of fQRSTa in patients with aortic stenosis undergoing surgical aortic valve replacement
Author(s) -
Erturk Mehmet,
Avci Yalcin,
Agus Hicaz Zencirkiran,
Guner Ahmet,
Demir Ali Riza,
Tasbulak Omer,
Aslan Serkan,
Yildirim Ceren,
Can Cemil,
Oz Kursad
Publication year - 2020
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.14858
Subject(s) - medicine , aortic valve replacement , cardiology , odds ratio , stenosis , perioperative , confidence interval , incidence (geometry) , aortic valve stenosis , retrospective cohort study , aortic valve , surgery , physics , optics
Background Surgical aortic valve replacement (sAVR) is the ultimate therapy for severe aortic stenosis (AS) in suitable patients. Prognostic factors of sAVR are great interest in recent studies. Frontal QRS‐T angle (fQRSTa) is a novel marker of ventricular repolarization abnormalities. In this study, we aimed to investigate the prognostic value of fQRSTa in patients with severe symptomatic AS undergoing sAVR. Methods A total of 372 patients with severe degenerative AS who underwent successful sAVR were included in this retrospective study. Then, patients were divided into two groups: patients with narrow fQRSTa (≤90°) as group 1 and wide fQRSTa (>90°) as group 2. Perioperative and postoperative clinical evaluation and time of death were recorded from all subjects. Results The incidence of total mortality was higher in patients with wider fQRSTa (13.8% [15]; 4.9% [9], P = .013) compared to patients with narrow fQRSTa. In multivariate logistic regression analysis, advanced age (odds ratio [OR] = 1.054; 95% confidence interval [CI] = 1.004‐1.106; P = .034), dyspnea (OR = 7.687; 95% CI = 2.296‐25.729; P = .001), lower efection fraction (OR = 0.924; 95% CI = 0.884‐0.966; P = .001), in‐hospital duration (OR = 1.051; 95% CI = 1.016‐1.088; P = .004) and wider fQRSTa (OR = 4.029; 95% CI = 1.383‐11.740; P = .011) were found to be independent predictors of mortality. Additionally, a Kaplan‐Meier survival analysis also revealed that long‐term survival was found to be significantly decreased in patients with wider fQRSTa (log‐rank P = .014). Conclusion fQRSTa was related with poor prognosis in patients with AS undergoing sAVR. fQRSTa was also an independent predictor of mortality in this population.