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Tropheryma whipplei endocarditis: An uncommon infection with potentially fatal consequences
Author(s) -
Muretti Mirko,
Keiralla Amar,
Jeffery Katie,
Krasopoulos George
Publication year - 2020
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.14467
Subject(s) - medicine , tropheryma whipplei , endocarditis , sepsis , antibiotic therapy , antibiotics , blood culture , infective endocarditis , surgery , whipple's disease , disease , microbiology and biotechnology , biology
We report a case of culture‐negative aortic valve endocarditis secondary to Tropheryma whipplei infection. Our patient underwent aortic valve replacement after 4 weeks of antibiotic therapy with persistently negative blood culture results. Despite a technically uneventful operation, the patient showed continued sepsis and was unresponsive to a broad‐spectrum of antibiotic therapy with subsequent multiorgan failure. He died on the 5th postoperative day, and diagnosis was established at postmortem examination. In this case report, we discuss the diagnosis and treatment of a rare type of endocarditis caused by T . whipplei .