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The effect of catheter‐directed thrombolytic use on readmission rates and in‐hospital outcomes among cancer patients with venous thromboembolism in the United States
Author(s) -
Guha Avirup,
McKinley Grant,
Dey Amit K.,
Carter Rebecca,
Miller P. Elliott,
Deshmukh Abhishek J.,
Zaghlol Raja,
Barac Ana,
Desai Nihar R.,
Addison Daniel
Publication year - 2020
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.14444
Subject(s) - medicine , venous thromboembolism , cancer , cohort , emergency medicine , intensive care medicine , thrombosis
Background Cancer inducing a hypercoagulable state, venous thromboembolism (VTE) remains a leading cause of morbidity and mortality globally. We assessed the impacts of cancer on the likelihood for readmission after a VTE‐targeted procedure. Methods We created a new cohort using discharge‐level data from all hospitalizations from State Inpatient Databases of geographically dispersed participating states (18‐27 states). Results In those presenting with VTE during index‐admission (619 241), 2.4% patients underwent catheter directed thrombolytic therapy (CDL) on index admission and among those 20.3% had cancer. Moreover, the 30‐day readmission rate amongst CDL recipients (10 776 overall) was 14.3% in those with cancer compared to 8.8% in those with no cancer history ( P < .0001). Additionally, in‐hospital mortality (5.7% vs 1.1%; P = 0.009) and cost‐of‐care ($11 014 ± 914 vs $10 520 ± 534; P = .04) was significantly higher in cancer compared to noncancer. Conclusion The use of CDL does not appear to reduce the risk of returning for a VTE‐related admission in cancer.