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Older patients with anomalous origin of the pulmonary artery from the ascending aorta: Guidance via lung biopsy
Author(s) -
Zhao Junfei,
Si MingSing,
Wang Xiaoyan,
Chen Siyao,
Yan Qian,
Chen Jimei
Publication year - 2020
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.14322
Subject(s) - medicine , ascending aorta , pulmonary artery , right pulmonary artery , lung , lung biopsy , cardiology , biopsy , cardiac catheterization , left pulmonary artery , radiology , aorta , candidacy , surgery , politics , political science , law
Abstract Anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital cardiac anomaly characterized by progressive pulmonary arterial hypertension (PAH) and pulmonary vascular obstructive disease (PVOD) in early childhood. This condition is assumed to be inoperable in older children and adults. However, pulmonary vascular resistance of the isolated lung is difficult to measure by catheterization due to its unique anatomical features, and thus we have used lung biopsy as an alternative method to evaluate candidacy for repair. Here, we report our experience with two patients whose lung biopsy demonstrated reversible PVOD, leading us to perform a surgical repair.