Rate of reoperation at 1 year for aortic repair vs replacement in aortic regurgitation. A trial sequence analysis of published meta‐analysis results

The pooled estimate of a recent meta‐analysis concluded that rate of reoperation at 1 year was significantly higher in Aortic valve repair (8.82% vs 3.70%) as compared with aortic valve replacement in patients with aortic regurgitation (odds ratio = 2.67, 95% confidence interval [1.08, 3.62], P  = .03). We performed a trial sequential analysis using the published data of the meta‐analysis and found the evidence is not strong enough for the conclusion.