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Bretschneider and del Nido solutions: Are they safe for coronary artery bypass grafting? If so, how should we use them?
Author(s) -
Siddiqi Shirin,
Blackstone Eugene H.,
Bakaeen Faisal G.
Publication year - 2018
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.13539
Subject(s) - medicine , bypass grafting , artery , dosing , cardiology , grafting , chemistry , organic chemistry , polymer
A variety of cardioplegic solutions are being used widely today to arrest the heart during coronary artery bypass grafting (CABG) and other cardiac operations. To minimize interruptions during the surgery for intermittent dosing of the cardioplegia and to facilitate less invasive cardiac procedures, single‐shot solutions, including Bretschneider and del Nido solutions, have been introduced. This review examines the evidence regarding the safety and efficacy of Bretschneider and del Nido cardioplegia during CABG. The findings support their use in routine low‐risk CABG, but finds insufficient evidence to support their safety in high‐risk surgeries.