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Electron Microscopic Comparison of Radial Artery Grafts in Non‐Diabetic and Diabetic Coronary Bypass Patients
Author(s) -
Gürsoy Mete,
Güzel Elif,
Ertürküner Pelin,
Çakır Idil,
Duygu Egemen,
Gülcan Füsun,
Hökenek A.Faruk
Publication year - 2016
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.12761
Subject(s) - medicine , glycemic , radial artery , diabetes mellitus , artery , cardiology , coronary artery disease , type 2 diabetes mellitus , type 2 diabetes , endocrinology
Objective We compared electron microscopic histologic changes of the radial artery grafts in non‐diabetic and diabetic patients. Methods Thirty‐six patients were divided into three groups according to their diabetic status (Group I had no diabetes mellitus [DM], Group II had type two DM and HbA1c levels were <7.5%, and Group III had type 2 DM but HbA1c levels were >7.5%). Distal parts of radial artery grafts were evaluated with scanning electron microscopy in a blind fashion by two histologists. Electron microscopic scores were compared among the groups. Results Radial artery electron microscopic scores were significantly different between group 1, 2 and 1, 3 and 2, 3 (p = 0.028, p < 0.001, and p < 0.001). In linear regression analysis, duration of DM (p = 0.027) and fasting plasma glucose (p = 0.001) were found as independent risk factors for histologic changes of radial artery grafts. Conclusion Duration of DM and poor glycemic control were found to be associated with radial artery electron microscopic changes. doi: 10.1111/jocs.12761 (J Card Surg 2016;31:410–415)