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Identification and Management of Atypical Hemolytic Uremic Syndrome Immediately Post–Heart Transplantation
Author(s) -
Vardas Panos N.,
Hashmi Zubair A.,
Hadi M. Azam
Publication year - 2015
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.12520
Subject(s) - medicine , calcineurin , atypical hemolytic uremic syndrome , heart transplantation , transplantation , heart disease , intensive care medicine , pediatrics , immunology , antibody , complement system
A BSTRACT Atypical hemolytic uremic syndrome (aHUS) is a serious hematologic disorder with high mortality if left untreated. A comprehensive literature review revealed only two cases of aHUS post–heart transplantation. In both cases the disease developed after induction of calcineurin inhibitor therapy. We report a case of immediate post–heart transplantation aHUS, manifested before the induction of, and therefore not associated with, calcineurin inhibitors. doi: 10.1111/jocs.12520 (J Card Surg 2015;30:373–375)