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Acute Heart Transplant Graft Failure in Association with Hyperosmolar Hyperglycemia State
Author(s) -
Sadat Kamel,
Morsy Mohamed,
Khalife Wissam I.
Publication year - 2014
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/jocs.12408
Subject(s) - medicine , ejection fraction , cardiology , ventricular assist device , heart failure , heart transplantation , cardiomyopathy , ischemic cardiomyopathy , transplantation , hemoglobin
We report a 38‐year‐old male with end‐stage ischemic cardiomyopathy requiring left ventricular assist device placement, followed by orthotopic heart transplantation, who presented 18 months post‐orthotopic heart transplant with acute graft failure with estimated left ventricular ejection fraction of 5% to 10%, in association with a glucose level of 550 mg/dL, and hemoglobin A1C of 13.8% and a negative pathology for a graft cellular and humoral rejection and no vasculaopthy. His left ventricular ejection fraction improved significantly to 40% to 45% within three days of optimal glucose control. doi: 10.1111/jocs.12408 (J Card Surg 2014;29:737–739)